Characterization of HBV Isolates from Patient Serum Samples and Cloning

Liang Cao, Chunchen Wu, Kaitao Zhao, Xinwen Chen
2015 Bio-protocol  
Hepatitis B virus (HBV) mutants can lead to vaccine failure, diagnostic failure of HBV detection, increase viral replication and resistance to antiviral agents. To study the biological characteristics of these mutations may contribute to our knowledge on viral pathogenesis. Therefore, it is essential to isolate and characterize HBV strains from patients.
doi:10.21769/bioprotoc.1683 fatcat:6jpoadqfjne5jp64zdcv5nv7su