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The Mechanics of Lung Tissue under High-Frequency Ventilation
SIAM Journal on Applied Mathematics
High-frequency ventilation is a radical departure from conventional lung ventilation, with frequencies greater than 2Hz, and volumes per breath much smaller than the anatomical deadspace. Its use has been shown to benefit premature infants and patients with severe respiratory distress, but a vital question concerns ventilator-induced damage to the lung tissue, and a clear protocol for the most effective treatment has not been identified. Mathematical modeling can help in understanding thedoi:10.1137/s0036139999363652 fatcat:dj4d74dsazeaho6kwn5ou4kxzu