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Lecture Notes in Computer Science
The Double Cut and Join (DCJ) is a generic operation representing many rearrangements that can change the organization of a genome, but not its content. For comparing two genomes with unequal contents, in addition to DCJ operations, we have to allow insertions and deletions of DNA segments. The distance in the so-called general DCJindel model can be exactly computed, but allows circular chromosomes to be created at intermediate steps, even if the compared genomes are linear. In this case it isdoi:10.1007/978-3-319-02624-4_4 fatcat:wavtm5iu4vhtvfa6n4glejfhdu