Phytochemical screening and In Vitro Antioxidant potential of Memecylon umbellatum Burm leaf extracts

Suresh G Killedar, Sachin S Mali, Harinath N More, Sameer J Nadaf, Sachin S Salunkhe, Raviraj S Karade
2014 Journal of Drug Delivery and Therapeutics  
Objective: Different dry extracts of Memecylon umbellatum Burm leaf obtained by various solvents such as petroleum ether, chloroform, ethyl acetate, acetone, methanol and chloroform water (IP) was screened to reap the benefits of its antioxidant and free radical scavenging properties using ascorbic acid as standard antioxidants. Methods: The in vitro free radical scavenging activity was evaluated using diphenyl picryl hydrazyl (DPPH) radical method using various concentrations of dry extract in
more » ... distilled water (1, 2, 4, 8, 16 , 20 μg/ml) against blank with ascorbic acid as a standard in same concentrations. Results: Among the all extracts, Methanol leaf extract has showed higher Antioxidant activity (84.65 ± 0.064 %) having IC 50 Value 11.81 ± 0.033 μg/ml at 20 μg/ml. While, IC 50 value for ascorbic acid was found to be 8.91 ± 0.084 μg/ml. Conclusion: The results clearly indicate that Methanol leaf extract of Memecylon umbellatum is effective in free radical scavenging. So in future, this may emerge as promising natural herbal source of powerful antioxidant.
doi:10.22270/jddt.v4i2.788 fatcat:ebemfnmarbfeno74jl4qgrkxqu