Small-cell Lung Cancer Exhibiting Spontaneous Regression

Shin-ichiro Iwakami, Mitsuhiro Fujii, Toshiji Ishiwata, Naoko Iwakami, Munechika Hara, Hiroaki Ihara, Ryo Wada, Takeo Tsutsumi, Kuniaki Seyama, Kazuhisa Takahashi
2013 Internal medicine (Tokyo. 1992)  
A 56-year-old woman was admitted to our hospital because a chest X-ray and thoracic computed tomography (CT) scan revealed a heterogeneous tumor in the middle mediastinum during a visit to a nearby clinic for a consultation regarding a persistent cough and body weight loss. However, the tumor spontaneously decreased on thoracic CT performed on admission. Subsequently, a biopsy of the tumor using video-assisted thoracoscopy was performed. The pathological findings disclosed the tumor to be
more » ... cell lung cancer with infiltration of CD8-positive T-cells exhibiting spontaneous regression. Cell-mediated immunity, including CD8-positive T-cells, may have relevance to the spontaneous regression of malignant tumors.
doi:10.2169/internalmedicine.52.0284 pmid:24088761 fatcat:f3we3uzribcofpu5xcyyybj2om