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Lecture Notes in Computer Science
Due to the high false positive rate in the high-throughput experimental methods to discover protein interactions, computational methods are necessary and crucial to complete the interactome expeditiously. However, when building classification models to identify putative protein interactions, compared to the obvious choice of positive samples from truly interacting protein pairs, it is usually very hard to select negative samples, because non-interacting protein pairs refer to those currentlydoi:10.1007/978-3-642-29627-7_33 fatcat:a6jyptgflrhafmla7cnrlepcda