823 Pharmacy KIDS – pharmacy students' knowledge identifying and managing minor ailments in children

Niamh M Brogan, Alice P McCloskey
2021 Abstracts   unpublished
intervention. Side effects of neonatal phototherapy are not serious and seems to be well controlled. The short-term side effects of phototherapy may include imbalance of thermal environment and water loss, electrolyte disturbance, bronze baby syndrome and circadian rhythm disorder and others. Objectives 1. To determine the risk factors of phototherapy induced short term side effects among icteric full term and preterm neonates. 2. To study frequency of phototherapy induced short term side
more » ... s in neonates with jaundice after 48 hours of continuous, double surface phototherapy or at the end of phototherapy, in case duration of phototherapy is less than 48 hours. Methods This study was hospital based prospective study and was conducted on 115 babies in their first week of life admitted to Neonatal Intensive Care Unit at governmental hospital (Om-Elmasreen general hospital in Giza governorate) with the diagnosis of unconjugated hyperbilirubinemia to receive phototherapy for 48 hours at least, in eight months period. All children were subjected to History taking for the mother and fetus, Clinical examination, CBC differential leucocytic count, Reticulocyte count, at initiation and after 48 hours of phototherapy, CRP, Plasma bilirubin level, at initiation and after 48 hours of phototherapy, Serum calcium level, at initiation and after 48 hours of phototherapy. Statistical analysis were done using SPSS version 21, using mostly Chi-square test and t-test. Results Forty-nine babies were found to have clinically detected phototherapy induced short-term side effects such as dehydration, diarrhea, hyperthermia, skin rash, abdominal distention, disturbance of the circadian rhythm. Laboratory changes were found such as hypocalcaemia, rising in Retics Rising in Platelet count rising in TLC. Many risk factors found to be significantly related to phototherapy induced short-term side effects; prematurity, mother illness in general during pregnancy, mother history of anemia, mother history of oligohydraminous, taking dexamethasone, delivery by caesarian section, physiologic skin desquamation.There is a significant difference in the occurrence of overall clinically observed side effect between full term and preterm babies. Side effects occurred in (72.0%) of preterm babies in comparison to (34.4%) of full-term babies with p-value 0.001 (p<0.05). There is a significant difference in between babies with hypocalcemia and babies without as regard gestational age, body weight on admission, body weight after phototherapy, head circumference, abdominal circumference on admission, abdominal circumference after phototherapy, heart rate after phototherapy. The lesser the gestational age, body weight on admission, head circumference, abdominal circumference on admission, abdominal circumference after phototherapy, the more the liability of occurrence of hypocalcemia. Conclusions . From this study, it could be concluded that phototherapy seems to have a clinically detected short-term side effect like dehydration, diarrhea, hyperthermia, skin rash, abdominal distention, disturbance of the circadian rhythm with jitteriness and laboratory detected short-term side effect like decline in serum calcium level, rising in Retics Count, rising in Platelet count, rising in TLC. However, it does not seem to have a deleterious effect on the babies and mostly these side effects disappear soon after stoppage of phototherapy.
doi:10.1136/archdischild-2021-rcpch.217 fatcat:mn5zj4ttpnbqzgp5wjdncqdlju