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Brain amyloid in virally suppressed HIV-associated neurocognitive disorder
2020
Neurology: Neuroimmunology & Neuroinflammation
ObjectiveTo determine whether virally suppressed HIV neuropathogenesis, a chronic neuroinflammatory state, promotes abnormal brain amyloid deposition.MethodsA total of 10 men with virally suppressed HIV-associated neurocognitive disorder (HAND), aged 46–68 years, underwent 11C-labeled Pittsburgh compound B PET. Data from the Australian Imaging, Biomarkers and Lifestyle (AIBL), including 39 cognitively normal individuals (aged 60–74 years), 7 individuals with mild cognitive impairment (MCI)
doi:10.1212/nxi.0000000000000739
fatcat:3edhrwdjkje4nakwmpgfftiyiy