Population data of five STRs from the INTERPOL series in a mestizo population of western Mexico (State of Jalisco)
Datos poblacionales de cinco STRs de la serie INTERPOL en una población mestiza del Occidente de México

Antonio Quintero-Ramos, Jorge R Padilla-Gutiérrez, Guillermo Hernández-Zaragoza, Yeminia Valle, Laura L Valdez-Velázquez, Norma Olivares, Fernando Rivas
Revista de investigación clínica  
Short tandem repeats (STRs) are the DNA polymorphisms most widely used in forensic genetics and parentage testing. Most common series of STRs are those from FBI (CODIS) and from INTERPOL. While there are data related to the first group, no studies are still known in Mexican populations in regard of the INTERPOL set. To describe the genetic characteristics of five INTERPOL STRs and to estimate their main forensic parameters in a population from western Mexico. Samples from 100 random volunteers
more » ... random volunteers from the State of Jalisco were PCR typed for STRs F13B, D2S1338, FESFPS, Penta D and Penta E. Genotype proportions in all five STRs were in agreement with Hardy-Weinberg expectations (p > 0.05). Heterocygosity varied from 0.68 for FESFPS to 0.91 for Penta E markers. Power of discrimination (PD) and exclusion probability (EP) were in the 0.83-0.97 and 0.46-0.75 ranges, respectively. The five combined STRs give a PE > 0.99143 and PD > 0.99999. These results contribute to establish data bases representative of western Mexico and are useful in DNA forensic and parentage studies.
pmid:19637724 fatcat:jhnix32jhfajtay45pjkdnpaoe