Insulin/Glucose Infusion Successfully Resuscitates Bupivacaine-induced Sudden-onset Circulatory Collapse in Dogs

M.H. Kim, K.H. Lee, C.S. Kim, S. Yang, T. Uugangerel, C.M. Kim, B.C. Kang
2014 Obstetric Anesthesia Digest  
Purpose In previous studies, insulin reversed the cardiac toxicity gradually induced by a continuous infusion of bupivacaine. In this randomized controlled study, we intended to simulate a more relevant clinical situation by injecting bupivacaine rapidly as a bolus to induce suddenonset circulatory collapse in dogs. We then evaluated the insulin effect. uthor contributions Mi-Hyun Kim, Kook-Hyun Lee, and Chong-Soo Kim helped design the study.
doi:10.1097/01.aoa.0000446313.41801.7e fatcat:bssh62wbnbg75mvcnartbpyntu