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Membrane protein dynamics studied by X-ray lasers – or why only time will tell
Current Opinion in Structural Biology
Membrane proteins are the gatekeepers of cellular membranes where they act as enzymes, transporters, signaling receptors, or in energy conversion. Traditionally seen as a difficult field, the last decade has brought dramatic progress to membrane protein structural biology. Here, I describe recent advances in studying the conformational dynamics of membrane proteins by X-ray free electron lasers. By integrating sample efficient high viscosity injectors into pump probe setups, it has becomedoi:10.1016/j.sbi.2019.02.001 pmid:30861431 fatcat:hmyni7ntv5hqbdkvrgeldw3ziq