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Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes
Nutrition research reviews
Glucose homeostasis is precisely regulated by glucagon and insulin, which are released by pancreatic aand b-cells, respectively. While b-cells have been the focus of intense research, less is known about a-cell function and the actions of glucagon. In recent years, the study of this endocrine cell type has experienced a renewed drive. The present review contains a summary of established concepts as well as new information about the regulation of a-cells by glucose, amino acids, fatty acids anddoi:10.1017/s0954422414000031 pmid:24721112 fatcat:eckedrmmfvd4thmnotlh7zkgge