Are dose calculations during dose optimization in brachytherapy necessary?

M. Lahanas, D. Baltas
2003 Medical Physics (Lancaster)  
We consider the problem of anatomy based dose optimization in brachytherapy. A calculation method for some o bjective functions and their derivatives is proposed which significantly reduces the number of required operations. The optimization in some cases, ignoring a preprocessing step, is independent of the number of sampling points. The idea is that some of the objectives and their derivatives used for dose optimization do not require the explicit calculation of dose values. Dose optimization
more » ... with the new modified computation method for the objectives and derivatives is, depending on the number of sampling points up to 100 times faster than the conventional method with dose calculation.
doi:10.1118/1.1580483 pmid:14528959 fatcat:yqcqmtcdnrhe7i6lagrbtjrcnm