Synthesis, characterization and anti-inflammatory activity of some novel pyrimidin-2-amines on Carrageenan-induced paw edema in balb/c mice

S Kumaresan, S Chandrasekaran, K Sakthivel, C Guruvayoorappan, Israel Enoch
We report here the synthesis of some new pyrimidin-2-amines and their anti-inflammatory activity against Balb/c mice with locally induced edema. Spectral characterization of the compounds is explained. The better drug candidate is optimized among the tested compounds.