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Pleuroperitoneal leak should be considered in the differential diagnosis of a pleural effusion, expecially in patients on peritoneal dialysis. The existence of a pleuro-peritoneal leak is demonstrated by pleural fluid analysis: a transudate with high glucose content similar to the dialysate, together with a normal concomitant blood glucose concentration. Treatments for dialysate leaks include a variety of approaches, depending on the severity of symptoms and signs. We report the case of a 77doi:10.4172/2165-7548.1000323 fatcat:6x5a566kgber3kngxopclvwye4