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Animal Models in Medicine and Biology [Working Title]
Now there is interest in finding factors that, once in the ovum, can affect the development of offspring. The sbr (Dm nxf1) gene in D. melanogaster belongs to the evolutionarily conserved family of nxf (nuclear export factor). It is involved in controlling of male fertility and forming the factor that affects the segregation of maternal and paternal chromosomes after fertilization. The Dm NXF1 (SBR) protein seems to play a role in forming this mysterious factor during the meiotic period ofdoi:10.5772/intechopen.90917 fatcat:xutmgr6rxjeyfng3hc2ruhyw6e