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Journal of Virology
The relationship between replication of simian virus 40 (SV40) DNA and the various periods of the host-cell cycle was investigated in synchronized CV1 cells. Cells synchronized through a double excess thymidine procedure were infected with SV40 at the beginning or the middle of S, or in G2. The first viral progeny DNA molecules were in all instances detected approximately 20 h after release from the thymidine block, independent of the time of infection. The length of the early, prereplicativedoi:10.1128/jvi.12.1.99-107.1973 fatcat:lwt4l2mwdzcxnontclvsd6panq