(201)Tl and (99m)Tc-MIBI retention in an isolated heart model of low-flow ischemia and stunning: evidence of negligible impact of myocyte metabolism on tracer kinetics

Adey Ayalew, Pierre-Yves Marie, Patrick Menu, Paul-Michel Mertes, Sandra Audonnet, Valérie Jouan, Pierre Olivier, Gilles Karcher, Dan Ungureanu-Longrois, Alain Bertrand
2002 Journal of Nuclear Medicine  
It is not known whether cellular metabolic disorders play a role in the decreased tracer uptake that is documented by conventional SPECT during low-flow ischemia or stunning. This study sought to determine the impact of low-flow ischemia and stunning on the kinetics of (201)Tl and MIBI across the plasma membrane of myocytes.
pmid:11937603 fatcat:5gen5md72fa2pdo6xenrl23ivy