ApoB/ApoA-1 ratio and nitric oxide levels in pregnancy induced hypertensive women

Visala Jammalamadaga, Philips Abraham, P. Sivaprasad
2016 International Journal of Research in Medical Sciences  
Pregnancy induced hypertension is considered as the major cause of maternal and perinatal mortality. Even though occurrence of PIH is due to abnormal placentation, endothelial dysfunction plays a pivotal role in the genesis of the multisystem disorder that develops in pre eclampsia and eclampsia. Various studies have proved that hyperlipidemia is one of the major causes of endothelial dysfunction. Since ApoB/apoA-I ratio is a dyslipidemic indicator, the study was designed to determine
more » ... determine ApoB/ApoA-I in PIH women and to analyse whether this ratio can be correlated with ED in PIH women. Methods: A cross-sectional analytical study involved normotensive, preeclamptic and eclamptic pregnant women with hundred subjects in each group. They were investigated for serum lipid profile, ApoA, ApoB, NO, MDA, FRAP in the 3rd trimester of pregnancy.
doi:10.18203/2320-6012.ijrms20160980 fatcat:bgv76sdxgjdjph6thxhi57vkum