Kinetics of dissolution of calcium oxalate monohydrate

Gary L. Gardner, George H. Nancollas
1975 The Journal of Physical Chemistry  
Human kidney stones consist mainly of calcium oxalate monohydrate (COM). The role of addition of some organic compounds in the kinetics of the dissolution process was investigated. These compounds are aniline (A), p. methyl amine (T), P-floro-aniline (FA) and their hydrazides AH, TA and FH. The amounts of these compounds vary between 10 and 10 . The results revealed that the dissolution process was effectively 5 6 retarded in presence of the organic compounds. The retardation effect followed
more » ... effect followed the sequence TH >A> FH > T > FA> AH. The possible adsorption of these compounds on the surfaces of COM crystals might decrease the concentration of active sites on COM leading to a decrease in the dissolution rate. The dissolution process was mainly controlled by surface process.
doi:10.1021/j100591a005 fatcat:2lxxfgbn5rfmbehm4vql37xwr4