Urinary S-PMA is a biomarker that is most specific and sensitive to benzene exposure at any concentrations because it is not influenced by the exposure of other substances. The objective of this study was to analyze the association between urinary SPMA and individual characteristics in workers exposed to benzene. This study used crosssectional design in five informal shoes industry in Cibaduyut. Urinary S-PMA level in 60 workers was determined using LC-MS/MS and individual characteristics data

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... ere collected by interview using questionnaires. The association between urinary S-PMA level and individual characteristics were analyzed using correlation (age and working time) and independent T-test (type of job, working hours per day, smoking status, and alcohol intake). The urinary S-PMA level from 33% workers was above BEI ACGIH (>25 µg/g creatinine). Types of job and working hours per day showed significant associations with urinary S-PMA level (p-value 0.036 and 0.033, respectively). Therefore, workers' urinary S-PMA level indicates the presence of benzene exposure in the workplace.