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Objectives: To identify asymptomatic boys with Xlinked adrenoleukodystrophy who have a normal magnetic resonance image (MRI), and to assess the effect of 4:1 glyceryl trioleate-glyceryl trierucate (Lorenzo's oil) on disease progression. Method: Eighty-nine boys (mean ± SD baseline age, 4.7±4.1 years; range, 0.2-15 years) were identified by a plasma very long-chain fatty acids assay used to screen at-risk boys. All were treated with Lorenzo's oil and moderate fat restriction. Plasma fatty acidsdoi:10.1001/archneur.62.7.1073 pmid:16009761 fatcat:ciu5k2dsq5d3flcqnyf356r3vu