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Unstable Maternal Environment, Separation Anxiety, and Heightened CO2 Sensitivity Induced by Gene-by-Environment Interplay
In man, many different events implying childhood separation from caregivers/unstable parental environment are associated with heightened risk for panic disorder in adulthood. Twin data show that the occurrence of such events in childhood contributes to explaining the covariation between separation anxiety disorder, panic, and the related psychobiological trait of CO 2 hypersensitivity. We hypothesized that early interference with infant-mother interaction could moderate the interspecific traitfatcat:el5wysjnvfej7mwki7pmsiggou