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Computational techniques have been adopted in medical and biological systems for a long time. There is no doubt that the development and application of computational methods will render great help in better understanding biomedical and biological functions. Large amounts of datasets have been produced by biomedical and biological experiments and simulations. In order for researchers to gain knowledge from original data, nontrivial transformation is necessary, which is regarded as a criticaldoi:10.4331/wjbc.v3.i2.27 pmid:22371823 pmcid:PMC3286791 fatcat:gr5azlohjffvrcqvd4mgv5k2yy