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It is now clear that in most animal tissues that have been thoroughly investigated the main pathway of terminral respiration takes place via the citric acid cycle as developed by Krebs (1940) , Green et al. (1948), and others. The mechanism of oxidative reactions of bacteria, however, is still confused because of the SUMMARY Cell-free extracts of Azotobacter vinelandii having the ability to oxidize acetate, pyruvate, and the acids of the citric acid cycle have been prepared by wet crush-[VOL. 63doi:10.1128/jb.63.5.605-617.1952 fatcat:uwwbpoxydngkjh7hjpzfpd5ivq