RESUMEN Chlamydophila abortus (Cp. abortus) es una bacteria causante del Aborto Enzoótico Ovino; la importancia zoonótica de Cp. abortus ocurre durante el manejo de animales enfermos. El presente trabajo estima la prevalencia de personas con anticuerpos contra Cp. abortus en grupos de riesgo laboral expuestos y los posibles factores de riesgo. Se condujo un estudio trasversal en dos grupos de personas expuestas. En el grupo A se incluyeron a 86 propietarios de rebaños y trabajadores. El grupo B

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... por 52 profesionales de Medicina Veterinaria. Los títulos de anticuerpos se determinaron mediante ELISAr y se aplicó un cuestionario a los participantes para establecer los factores de riesgo. La prevalencia de anticuerpos contra Cp. abortus en productores y profesionistas fue de 6.52% (IC 95% 3.02-12.01%). Por grupo de riesgo la prevalencia en productores fue de 4.45% (IC 95% 1.28-11.48) y en profesionistas 9.62% (IC 95% 3.19-21.02), en mujeres 5.07% (IC 95% 1.99-11.29) y 1.44% en hombres; sin mostrar diferencias (P > 0.05). Se concluye que la prevalencia de anticuerpos frente a Cp. abortus en profesionistas y productores de ovinos es baja y los factores de riesgo no mostraron diferencias significativas. Palabras Clave: Chlamydophila abortus; ovinos; prevalencia; salud pública; zoonosis. SUMMARY Chlamydophila abortus (Cp. abortus) is the bacterial etiologic agent of the ovine enzootic abortion; zoonotic relevance rises during handling of ill animals. The present work estimates the prevalence of serum antibodies against Cp. abortus in groups of people at risk of infection derived from working activities, and estimates possible risk factors involve in the infection. A transversal study was conducted in two groups of exposed people. In Group A 86 sheep flock owners or workers were included. In Group B 52 veterinary doctors were included. Antibody titers were determined by rELISA assay, additionally it was asked to people sampled to answer a questionnaire to establish risk factors. Overall serum antibody prevalence against Cp. abortus in both groups was 6.52% (IC 95%, 3.02-12.01%). According to the risk group, people from group A was 4.45% (IC 95% 1.28-11.48) and in group B 9.62 (IC 95% 3.19-21.02), according to gender prevalences were 5.07% (IC 95% 1.99-11.29)and 1.44% for women and men respectively; no differences were found (P>0.05). It is concluded that serum anti Cp. abortus antibody prevalence in relatively low among sheep flock owners, workers and veterinarians and no significant differences were found among possible risk factors.