Human and spatial-temporal clustering analysis of human brucellosis in mainland China from 2012 to 2016
Objective: The aim of the present study was to better understand the epidemiology of brucellosis in mainland China. We set out to investigate the human, temporal and spatial distribution and clustering characters of the disease.Methods: Human brucellosis data from mainland China between 2012 and 2016 were collected from the China Information System for Disease Control and Prevention. A geographic information system ArcGIS10.3 (ESRI, Redlands) and SaTScan software were used to identify potential
... changes in the spatial and temporal distribution of human brucellosis in mainland China during the study period.Results: A total of 244,348 cases of human brucellosis were reported during the study period. During 2012-2016, the average incidence of human brucellosis was higher in the 40-60 age group. The temporal clustering analysis showed that the high incidence of brucellosis occurring between march and July annually. The spatial clustering analysis of the incidence of human brucellosis showed that the location of brucellosis clustering in mainland China remained relatively fixed, mainly concentrated in most parts of northern China. The results of spatial-temporal clustering analysis showed that the primary cluster located in northeast of China, including Inner Mongolia, Heilongjiang, Jilin and Liaoning, and the high-risk time was from January 2012 to December 2013.Conclusion: Human brucellosis remains a widespread challenge, particularly in northern China. The clustering analysis highlights potential high-risk human, time and areas which may require special plans and resources for monitoring and controlling the disease.