Determining a Detectable Threshold of Signal Intensity in cDNA Microarray Based on Accumulated Distribution

Xia Gao, Xuping Fu, Tao Li, Jian Zi, Yao Luo, Qing Wei, Erliang Zeng, Yi Xie, Yao Li, Yumin Mao
2003 BMB Reports  
In microarray data mining, one of the key problems is how to handle weak signals. Based on a bent piecewise linear accumulated distribution generally found in the microarray data, a new detectable threshold finding method is proposed to filter genes with unreliable information in this paper. More reliable and reproducible data is produced for the subsequent data mining.
doi:10.5483/bmbrep.2003.36.6.558 pmid:14659074 fatcat:z2gpljpcczaczhkbzpukqor7le