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Hydrodynamic mix can significantly degrade thermonuclear burn rate in an inertial confinement fusion (ICF) target. Successful mitigation requires a detailed understanding of the physical mechanisms by which mix affects burn. Here we summarize the roles of three distinct plasma physics effects on burn rate. The first is the well-known effect of enhanced thermal energy loss from the hot spot and the mitigating role of self-generated or externally-applied magnetic field. The second is the fuel iondoi:10.1088/1742-6596/688/1/012123 fatcat:fkurzlf72jac3n7qlrpodvxdu4