Developing in vitro Assays to Transform Gastrointestinal Safety Assessment: Potential for Microphysiological Systems

Matt Peters, Allison Choy, Carmen Pin, Derek Leishmann, Annie Moisan, Lorna C Ewart, Peggy Guzzie-Peck, Radhakrishna Sura, Douglas Keller, Clay W Scott, Kyle Kolaja
2020 Lab on a Chip  
Drug-induced gastrointestinal toxicities (DI-GITs) are among the most common adverse events in clinical trials. High prevalence of DI-GIT has persisted among new drugs due in part to the lack of...
doi:10.1039/c9lc01107b pmid:32129356 fatcat:jj7id6qywjaa3mmwch36yjlwhi