The effects of bromazepam on the early stage of visual information processing (P100)

Fernanda Puga, Isabel Sampaio, Heloisa Veiga, Camila Ferreira, Maurício Cagy, Roberto Piedade, Pedro Ribeiro
2007 Arquivos de Neuro-Psiquiatria  
The early stages of visual information processing, involving the detection and perception of simple visual stimuli, have been demonstrated to be sensitive to psychotropic agents. The present study investigated the effects of an acute dose of bromazepam (3 mg), compared with placebo, on the P100 component of the visual evoked potential and reaction time. The sample, consisting of 14 healthy subjects (6 male and 8 female), was submitted to a visual discrimination task, which employed the
more » ... ployed the "oddball" paradigm. Results suggest that bromazepam (3 mg) impairs the initial stage of visual information processing, as observed by an increase in P100 latency.
doi:10.1590/s0004-282x2007000600006 pmid:18094853 fatcat:sop2mzwgk5dnhncifxixtwu64a