Genomic Common Data Model for Seamless Interoperation of Biomedical Data in Clinical Practice: Retrospective Study (Preprint)

Seo Jeong Shin, Seng Chan You, Jin Roh, Jang-Hee Kim, Seokjin Haam, Christian G. Reich, Clair Blacketer, Dae-Soon Son, Seungbin Oh, Yu Rang Park, Rae Woong Park
2018 Journal of Medical Internet Research  
Clinical sequencing data should be shared in order to achieve the sufficient scale and diversity required to provide strong evidence for improving patient care. A distributed research network allows researchers to share this evidence rather than the patient-level data across centers, thereby avoiding privacy issues. The Observational Medical Outcomes Partnership (OMOP) common data model (CDM) used in distributed research networks has low coverage of sequencing data and does not reflect the latest trends of precision medicine.
doi:10.2196/13249 pmid:30912749 pmcid:PMC6454347 fatcat:75jz7rfiy5b4beasdvc7g2bdoy