A SIMPLE, EFFICIENT AND SOLVENT FREE ONE POT SYNTHESIS OF 3, 3 DIHETEROAROMATIC OXINDOLE

Shahed Ali Syed, Farooqui Maqdoom, Sultan Sayyad
2016 International Research Journal of Pharmacy  
Formic acid catalyzed, single step and environmentally friendly process for synthesis of 3, 3-diheteroaromatic oxindole derivatives is described. This adopted protocol for Friedel-Crafts substitution reaction has the advantage of reusability of the catalyst, high yields and ease of separation of pure products.
doi:10.7897/2230-8407.04431 fatcat:uwxbpgnfknc6tka2tbqib4hnn4