A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
The Sleeping Beauty Transposable Element: Evolution, Regulation and Genetic Applications
Current Issues in Molecular Biology
Members of the Tc1/mariner superfamily of transposable elements isolated from vertebrate species are inactive due to the accumulation of mutations. A representative of a subfamily of fish elements estimated to be last active >10 million years ago has been reconstructed, and named Sleeping Beauty (SB). This element opened up new avenues for studies on DNA transposition in vertebrates, and for the development of transposon tools for genetic manipulation in important model species and in humans.doi:10.21775/cimb.006.043 fatcat:jc2yxfb325atllzgefrz4mj3nm