N,N-Dimethylglycine in patients with progressive multiple sclerosis: result of a pilot double-blind, placebo, controlled randomized clinical trial

Thomas Wolfsegger, Klaus Böck, Wolfgang Schimetta, Tim J. von Oertzen, Hamid Assar
2021 Neurological Research and Practice  
AbstractOral administration of N,N-Dimethylglycine (DMG), a tertiary amino acid, presumably enhances oxygen utilization by tissue and complex with free radicals. Beneficial effects are improved endurance performance and reduction fatigue in humans and animals. This pilot study reports the results over a one-year double-blind, placebo-controlled trial of DMG in 30 randomized patients with progressive multiple sclerosis. No treatment effects were found between the placebo group and the DMG group
more » ... and the DMG group for disability, fatigue, cognitive, or gait parameters.
doi:10.1186/s42466-021-00126-z pmid:34024278 fatcat:rsrbpo4yfratpegiupah4odlma