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Rapid Tranquilization of Severely Agitated Patients With Schizophrenia Spectrum Disorders
Journal of Clinical Psychopharmacology
Agitation is a major problem in acute schizophrenia. Only a few studies have tested antipsychotic agents in severely agitated patients, mainly because of legal issues. Furthermore, most studies were limited to the first 24 hours. We aimed to investigate the efficacy of oral haloperidol, risperidone, and olanzapine in reducing psychotic agitation in severely agitated patients with schizophrenia or schizophreniform or schizoaffective disorder over 96 hours using a prospective, randomized,doi:10.1097/jcp.0000000000000050 pmid:24346752 fatcat:reg747nwxnfl5bvgnrsddwxopu