Prevalence and clinical correlates of miocardial fibrosis and necrosis in thalassemia major patients by CMR-DE

Alessia Pepe, Vincenzo Positano, Brunella Favilli, Daniele De Marchi, Giuseppe Rossi, Luigi Natale, Gennaro Restaino, Gianluca Valeri, Francesca Ferrara, Massimo Lombardi
2009 Journal of Cardiovascular Magnetic Resonance  
Myocardial siderosis is the main cause of morbidity and mortality in thalassaemia major. In the United Kingdom approximately 50% of patients die before reaching 35 years. The cardiomyopathy is reversible if chelation is commenced early but diagnosis is often delayed due to the late onset of symptoms. T2* CMR can now assess cardiac iron O3 Sub-clinical systolic dysfunction with persistent myocardial edema and inflammation in elite high-endurance athletes with common colds: a cardiovascular magnetic resonance study
doi:10.1186/1532-429x-11-s1-p241 fatcat:frwznwudjbejppzknmk3h2ng2a