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The use of a vaccine and Wolbachia bacterium have been proposed as new strategies against dengue. However, the performance of Wolbachia in reducing dengue incidence may depend on the Wolbachia strains. Therefore, in this paper, the performance of two Wolbachia strains which are WMel and WAu, in combination with the vaccine, has been assessed by using an age-dependent mathematical model. An effective reproduction number has been calculated using the Extended Kalman Filter (EKF) algorithm. Thedoi:10.3390/math10122075 doaj:1d3cc405e4194dff9f3c34967df54dab fatcat:yyhj5jvavvaxxh3lot5dkzl47i