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AbstractBreast cancer is the most prevalent cancer in women worldwide. Numerous studies have suggested that the E-cadherin adhesion system is dysregulated in cancer cells. These impaired functions of E-cadherin contribute to releasing cancer cells from the primary lesion to cell dedifferentiation. Some studies have shown that polymorphism may affectdoi:10.1515/biol-2016-0015 fatcat:qc3go7jmmrfo7liu4bbnkvzrhy