This paper presents a shunt active power filter performances based on threelevel (NPC) inverter using conventional pulse width modulation (PWM) and Ann's controllers to mitigate current harmonics generated by non-linear loads. Shunt APF is the best solution to eliminate harmonics drawn from nonlinear load especially for low power system, the conventional scheme based on the two level inverter controlled by hysteresis controller presents several drawbacks such us high inverse voltage applied to

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... ower components, degraded output voltage inverter waveforms, etc. Today three-level (NPC) inverter and intelligent controllers are widely used in different industrial applications. To take advantages of these inverter topology and artificial intelligent controller performance a novel control scheme based on Ann's current controller is proposed in this work. The control strategy adopted is the synchronous current detection method, it is easy to implement and permits a good extraction of reference currents compensation. The numerical simulation is performed using MATLAB-Simulink and SimPowerSystem Toolbox. The simulation results obtained in steady and transit states show the effectiveness and the superiority of Ann systems compared to PWM controller.