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Colorimetric Determination of Cefadroxil and Ceftriazone in Pharmaceutical Dosage Forms
Tropical Journal of Pharmaceutical Research
Purpose: To develop a simple, rapid and selective method for the spectrophotometric determination of cefadroxil and ceftriaxone using 1, 2-napthaquinone-4-sulfonic acid sodium. Methods: The method was based on the derivatization of cefadroxil and ceftriaxone with 1, 2naphthaquinone-4-sulfonic acid sodium in alkaline medium to yield orange-colored products. Results: The reaction products of cefadroxil and ceftriaxone at their respective λ max of 475 and 480 nm showed linearity in thedoi:10.4314/tjpr.v10i1.66546 fatcat:p5zjy3qspnf5pg4j6otzrtuey4