Original Article Clinical features of 99 patients with huge (size ≥6 cm) adrenal incidentaloma

Zhipeng Gao, Chuize Kong, Zhe Zhang, Xiaojun Man, Weiping Teng
2016 Int J Clin Exp Med   unpublished
Objective: With the development of radiological techniques, the diagnostic yield of adrenal incidentaloma reveals a significant rising trend. However, within the established diagnosed cases, the incident of huge adrenal incidentaloma (HAI) still remains to be rare. Here, we reported a large sample size of HAI with the analysis of clinical features. Methods and materials: 99 patients with an adrenal mass who were discovered incidentally by computed tomography (CT) or ultrasound (US) and were
more » ... d (US) and were undertaken for further general examination or nonadrenal disease from January 2005 to December 2014 were studied retrospectively. The age, sex, location and size of masses, blood pressure, fasting glucose, concomitant symptoms, functionality, reasons for detection, imaging, histological findings and the follow-up for all patients were described. Results: Target patients consist of 54 males (54.54%) and 45 females (45.45%), aged between 18 and 77, and the average age was 45.75 years old. Adrenal masses were mostly found in patients in their sixth decade (31.31%). 49.49% of masses were found in right adrenal gland, 47.47% were found in left, and 3.03% were found bilaterally. The sizes of the masses range from 6 to 15 cm with an average size of 8.09 cm. All patients underwent surgical resections. Pheochromocytoma (35.35%) was the largest part of the final postoperative histopathologic diagnosis, followed by malignant masses (21.21%). Conclusion: The features of benign, malignant, non-functional and functional adrenal masses in our huge adrenal incidentaloma that were incidentally found and diagnosed at our hospital were presented in this paper. Most of the features were similar to those from previous reports about CAI.