Methods of enhanced light transmission through turbid biological media [article]

Eric K. Chan, Jennifer K. Barton, Ashley J. Welch, Austin, The University Of Texas At, Austin, The University Of Texas At
A new process to increase light transmission in biological tissue has been developed. The technique involves temporarily replacing tissue water with a fluid that has a refractive index closer to that of inter/intra cellular components. Subsequently, the amount of index mis-match between these components and the fluid environment is temporarily decreased. This lowers the amount of random reflection and refraction which also reduces light scattering. In addition, the infrared absorption is
more » ... when the fluid has a lower absorption coefficient than water. Furthermore, this process is reversible; thus creating a transient window to enhance light transmission for therapeutic and/or diagnostic applications.
doi:10.26153/tsw/4349 fatcat:axwojfvkpjah7eq4zycdehzmzm