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Physiological effects of a bactericidal protein from human polymorphonuclear leukocytes on Pseudomonas aeruginosa
1986
Infection and Immunity
The physiological changes seen in Pseudomonas aeruginosa after exposure to a bactericidal protein (BP) from the granules of human polymorphonuclear leukocytes were studied. It was demonstrated, using radiolabeled proline or leucine, that both the rate of cellular uptake and amino acid incorporation into trichloroacetic acid-insoluble material were markedly decreased immediately after exposure to BP. The rate of 02 consumption by P. aeruginosa was decreased immediately after exposure to BP and
doi:10.1128/iai.52.1.90-95.1986
fatcat:xdgkdkkgyjetdpwufvth2dyhqi