Mucinous Adenocarcinoma Of Colon Presenting As Cutaneous Metastases Over The Abdominal Wall: A Rare Entity On Cytology

Gireesha Rawal, Mukul Singh, Charanjeet Ahluwalia, Ashish Kumar Mandal
2017 Annals of Pathology and Laboratory Medicine  
Discussion Skin metastases from colorectal adenocarcinoma generally occur within the first two years after resection of the primary tumor and often present simultaneously with metastases to ABSTRACT Skin metastases from colorectal carcinoma are rare and typically signify widespread disease with poor prognosis. We present two cases of a 55years old man and a 57 years old lady, both presenting with multiple skin nodules on the abdominal wall. FNAC smears of both the cases showed clusters and
more » ... s of atypical cells with moderate amount of cytoplasm against a necrotic background. Nuclei were round to oval with coarse chromatin and prominent nucleoli. Well formed glandular structures were seen. Immunocytochemistry showed that cells were positive for Muc-1, and negative for vimentin and LCA. A diagnosis of adenocarcinoma presenting as cutaneous metastasis was given. Detailed history, showed that both the patients were known cases of adenocarcinoma colon post chemotherapy and radiotherapy. Colorectal carcinoma presenting as cutaneous metastases is rare and FNAC is a noninvasive and fast method for directing towards the diagnosis of cutaneous metastasis in the patients with a known malignancy without any complication.
doi:10.21276/apalm.2017.1070 fatcat:2k7yjhgwnnbwjo5hlswjdg2wji