Random model approach for QTL mapping in half-sib families

Mario L Martinez, Natascha Vukasinovic, Gene AE Freeman
1999 Genetics Selection Evolution  
An interval mapping procedure based on the random model approach was applied to investigate its appropriateness and robustness for QTL mapping in populations with prevailing half-sib family structures. Under a random model, QTL location and variance components were estimated using maximum likelihood techniques. The estimation of parameters was based on the sib-pair approach. The
doi:10.1186/1297-9686-31-4-319 fatcat:7wozoobfqndtlco2zr5nfdvriu