Journal of Palliative care and Pediatrics Mini Review Open Access

Marianne Frieri, Krishan Kumar, Anthony Boutin, Marianne Frieri
2017 unpublished
The purpose of this article is to understand pediatric sepsis, activation of the innate immune system and a synergistic relationship between the loss of organ functions and sepsis pathophsiology. Many complex factors such as genetics, physical agents, mediators and effectors are involved in the development of organ failure both in sepsis in children and neonates. The patient's immune surveillance could fail to eliminate the pathogens with a release with inappropriate activation. These topics
more » ... very important for pediatricians, immunologists, and neonatologists.