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Seeds of Strychnos nuxvomica Linn. (Loganiaceae), a poisonous plant drug, is being used in different Ayurvedic therapeutics after proper processing (Shodhana) with some specific media. As per the available references in Ayurvedic classics, media like cow's urine, cow's milk, cow's ghee etc. has been incorporated for processing of Nux-vomica seeds. Apart from the classical methods some other methods are also implemented by the traditional practitioners of Ayurveda using castor oil (Erandafatcat:uszixuk2zzc4fp4jywh2jidunm