Clinical Evaluation of Sai-boku-to (kanpo medicine) for glossodynia TAKEYA YAMADA1 , KAZUHISA BESSH02, KENICHIRO MURAKAMI2 SHINSUKE HORI3, TADAHIKO IIZUKA2 and NATSUKI SEGAMI1 This study was conducted to asses the clinial efficacy of Sai-boku-to (Kanpo) in comparison to minor tranquilizer with vitamin B complex medication for the treatment of glossodynia. Either Sai-boku-to (7.5g per day) of minor tranquilizer (Diazepam) 6mg per day with vitamine B complex medication for three months was P . O.

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... administered to 104 cases. The clinical examination was carried out in order to evaluate the subjective symptoms such as pain, heat sensation , and unpleasent feeling in comcomitant treatment of glossodynia. After three-month administration the success rates were 75 .8 %, 87.1 %, and 88.7 % in the Sai-boku-to medication group and 73 .8 %, 71.4 %, 69.0 % in the minor tranquilizer medication group. The Sai-boku-to medication group was significantry superior to the minor tranquilizer medication group . The side effect of the sleepiness was found in 13 cases in the minor tranquilizer medication group . On the contrary, a mild signs and symptoms of digestive discomfort was noted in three cases in the Sai -boku-to medication group. These results suggested that Sai-boku-to was a clinically useful drug for the treatment of glossodvnia.