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No Association between the CDX2 G543C Polymorphism and Risk of Gastric Atrophy and Cancer
2012
Asian Pacific Journal of Cancer Prevention
Ectopic expression of CDX2 in the stomach is closely associated with chronic Helicobacter pylori (H. pylori) infection and intestinal metaplasia. Whether CDX2 has tumor suppression or tumorigenesis potential remains to be elucidated. In this study, we investigated the association between the CDX2 G543C polymorphism (silent mutation) and the risk for H. pylori-induced gastric atrophy and cancer as well as H. pylori infection, using 454 Japanese subjects undergoing a health checkup and 202
doi:10.7314/apjcp.2012.13.11.5691
fatcat:4olkwz4qr5copnfe6w3fgxrtie